The Brewers will send right-hander Marco Estrada to the mound to try to get back to their own winning ways.
Estrada is winless in 13 starts this season and has seen four potential victories blown by the shaky Brewers bullpen. After allowing one run in six innings Sunday against the Cardinals and still taking the loss, Estrada said he wasn't concerned with getting a win as long as he pitched well.
"If I just keep my team in the game, that's all I really care about," said Estrada. "I know I say that all the time, but I don't worry about if we're gonna score runs or not, because I think that will mess with my head a bit. I just go out and make the pitches, and hopefully things work out."
Rookie left-hander Dallas Keuchel will make his ninth Major League start Saturday. Unlike Estrada, Keuchel has a win this season, but has lost his last four decisions, including a loss to Milwaukee.
Keuchel is looking forward to facing the Brewers again after giving up seven runs in four innings in a start against them July 30. Keuchel said his command is much better right now.
"Honestly, I wasn't even around the plate," Keuchel said. "I had six walks. That's not what I want to do. They're going to see a different guy tomorrow. It's good that I'm going to be facing Milwaukee when they saw me at my worst. Maybe this time, they'll see me at my best."
Astros: New additions make debut
The Astros made a pair of roster moves before Friday's series opener against the Brewers, calling up outfielder Fernando Martinez and adding infielder Tyler Greene to their roster after a trade with the Cardinals.
Greene made his Astros debut Friday, pinch-running in the ninth inning and scoring the tying run in the Astros' 4-3 comeback win.
Martinez started in left field and went 0-for-3.
Brewers: Roenicke says his team not taking the Astros lightly
The Brewers arrived in Houston this weekend coming off a sweep of the division-leading Reds and feeling confident. But manager Ron Roenicke cautioned that if they didn't focus on beating the Astros, they could easily get tripped up.
Friday night, the Astros scored three runs in the last two innings and beat the Brewers, 4-3.
"If it's a Major League team, it can beat you," Roenicke said. "This team [the Astros], they always seem to hit the ball well against us. Every inning, I look up and there's somebody else on base. It doesn't take much to bust open a big inning when you get a lot of baserunners.
"We're not taking these games lightly, that's for sure."
Left fielder Ryan Braun went 2-for-4 in the Brewers 4-3 loss Friday and remains one stolen base shy of his third career 20 home run, 20 stolen base season.
Braun is hitting .307 and has 29 home runs and 19 stolen bases this season. His previous 20-20 seasons were in 2009 (32 homers, 20 steals) and 2011 (33 homers, 33 steals).
The Brewers have lost 10 straight road games. It is the fourth time in franchise history they've lost at least 10 road games in a row and the first since a 10-game skid in 1992.