The 29-year-old was born in Corona, Calif., and makes his offseason home in Beaumont, Calif. He purchased 50 tickets for family and friends, and another 50 friends of his are expected at the game.
On Saturday, he had breakfast with his family, whom he secured rooms for at the team hotel.
The righty is coming off a superb Golden State outing in his previous start. Nolasco defeated the Giants in San Francisco by throwing 7 1/3 innings of seven-hit, one-run ball.
In his career, Nolasco is 7-2 with a 2.55 ERA pitching in California, including a 3-1 record at Petco Park.
"I don't know what it is. I don't know," he said on pitching in his home state. "I've been pitching well on the West Coast. I hope to do what I'm doing. I'm trying to work as quickly as possible, get quick outs and go deep into games."
Nolasco will receive some extra help as Logan Morrison, who was out of the starting lineup on Friday and Saturday to rest his sore right knee, is expected to start on Sunday.
On the other side, Joe Wieland will start for the Padres, looking for his first career win in his fifth start.
His last time out, the 22-year-old worked five innings against the Brewers, but allowed five runs while striking out a career-best eight.
Most of the offense he allowed came by way of Ryan Braun, who hit two of his three homers in the game against Wieland.
"The biggest thing with this game is this was a big learning experience for me," Wieland said. "A great hitter like him is going to make adjustments pitch to pitch and at-bat to at-bat."
Padres: Street to DL
San Diego lost, 9-8, in extra innings on Friday, but the bigger loss came in the form of closer Huston Street going on the 15-day disabled list Saturday with a strained right latissimus dorsi muscle.
"Any time you strain a muscle, whether it's your hammy, your calf, those are muscle tears," manager Bud Black said. "They heal, but they take time, so it just depends on the severity of the strain. And this is a strain that is significant enough to go on the DL and rest and there's rehab. I'm going to venture to say he won't pitch the day he comes off the DL, so it'll be more than 15 days. It's not one of those where he'll be ready in 15 days."
Street had allowed one run in 9 2/3 innings, posting a 0.93 ERA and converting each of his four save opportunities.
"I've done this enough now to just take it day by day," Street added. "When you go on the DL, you know you have 15 days. We'll reevaluate in 15 days. I wish it could be quicker."
In a corresponding move, San Diego selected right-handed reliever Miles Mikolas from Double-A San Antonio. Mikolas made his debut Saturday night, allowing a solo homer to Miami's Giancarlo Stanton in the ninth inning.
Marlins: Bell removed from closer role
After Heath Bell blew his fourth save in seven chances this season on Friday night, manager Ozzie Guillen informed him on Saturday that he would use him earlier than in save opportunities for now.
"We're going to move him down for a few days to get him back on track," Guillen said. "It's not like we're removing him from his job. I made it clear to him that if we're going to be the club we should be, it's easier for him to be where he's supposed to be."
Bell has an 11.42 ERA through 8 2/3 innings this season while giving up 15 hits and walking 10.
As part of a rehab assignment with Triple-A Tucson, Carlos Quentin has gone 4-for-8 with a home run, three RBI, three runs scored and one walk in three games as of Saturday.
Stanton hit his fifth homer on Saturday in the ninth, extending his hitting streak to eight games.