Sitting three games back of Atlanta with a record of 11-12 and 3 1/2 behind of the division-leading Nationals, Philadelphia will turn to left-hander Cole Hamels, who has won his last three starts.
Hamels dominated the D-backs on Wednesday, retiring 18 consecutive batters at one point during an eight-inning start in which he allowed just two runs on four hits, while striking out seven in eight innings.
"He had 17 different pitches and threw them all for strikes," Arizona shortstop Willie Bloomquist said after the game. "He's good at what he does, and when he locates, he's awfully tough. You have to hope he makes a mistake and hope you don't miss it. He didn't make a lot of mistakes."
Hamels will be up against Braves right-hander Brandon Beachy, who has also been in a groove. Beachy has thrown into the seventh inning during his last three starts, in which he combined to give up only three runs. He has won his last two decisions.
His streak of 19 2/3 consecutive innings without allowing an earned run ended on Wednesday against the Dodgers, with the righty surrendering two earned runs on seven hits in 6 1/3 innings.
Phillies: Lee not ready to return Friday
While Cliff Lee is feeling better and is eligible to come off the disabled list on Friday with a strained left oblique, he won't be activated.
Still needing to throw two bullpen sessions before his start, which haven't been scheduled, Lee and the Phillies are taking a cautious approach.
"It's better," Lee said. "It's slowly getting better."
Braves: Heyward rests with soreness near oblique
Jason Heyward woke up Monday with soreness around his right oblique muscle, and he will rest until the Braves feel confident that he won't suffer a strain that could keep him out longer than a few days.
"With those things, I didn't want to mess with it," Braves manager Fredi Gonzalez said while explaining why Heyward wasn't in the starting lineup for Monday series finale against the Pirates.
Jair Jurrjens tossed seven solid innings for Triple-A Gwinnett against Toledo on Sunday in his first start since he was demoted last week.
"He did some things well," Braves assistant general manager Bruce Manno said. "It's a process, but it's encouraging to see him go out and do well and work on some things. He's accepted it really well. That's a big part of it."
The Phillies are 8-2 this season when scoring first and 3-10 when their opponent scores first.
Hamels went 2-1 with a 2.90 ERA in four starts last season against the Braves.
Braves shortstop Tyler Pastornicky hit safely is six straight games and in nine of his last 10 starts.